Banani Lab

The Banani Lab broadly investigates the disruption of cellular structure and physiology in various diseases to understand normal cellular functions and to enable new therapeutic strategies. We specialize in studying biomolecular condensation—a fundamental process cells use to organizing biochemical reactions into compartments through phase separation. These compartments, known as condensates, are disrupted in numerous diseases, ranging from cancers to rare genetic disorders. We leverage approaches from cell biology, genetics, biophysics, and pathology to glean fundamental principles of how condensates function by studying how they are disrupted in disease.